William Curtis Baer, II,Michael Joseph Passariello
申请号：
US14757886
公开号：
US20160175296A1
申请日:
2015.12.23
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A method of forming a liquid formulation includes preparing a mixture and adding a second component to the mixture to form the liquid formulation. The mixture includes water, a film-forming polymer, a buffer, and a first component. The first component is an active ingredient including buprenorphine or a sweetener. The second component is the active ingredient comprising buprenorphine or the sweetener. Adding the second component is the last step in creating the liquid formulation. If the first component is the active ingredient, the second component is the sweetener. If the first component is the sweetener, the second component is the active ingredient. A method of forming a water-disintegrable film includes casting a formulation film from the liquid formulation and drying the formulation film to form the water-disintegrable film. A film formulation and a water-disintegrable film are also disclosed.
