Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells

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专利权人:

Zee Fen Chang

发明人:

Zee Fen Chang,Jim-Min Fang,Chun-Mei Hu,Ming-Tyng Yeh

申请号：

US13990398

公开号：

US09278982B2

申请日:

2011.11.29

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to novel TMPK inhibitor compositions and their methods of use. In particular, it relates to novel TMPK inhibitor compositions and therapeutics that lead to dUTP-mediated DNA repair in tumor cells and acts as a novel chemosensitizer, which are useful in methods for treating or preventing cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/