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Immediate-release tablets containing combimetinib and methods of making and using the same
专利权人:
Genentech; Inc.
发明人:
Sanjeev Kothari,Priscilla Mantik,Alexander Mauerer,Hamid Rezaei
申请号:
US15852125
公开号:
US10478400B2
申请日:
2017.12.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
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