PROBLEM TO BE SOLVED: To provide a new vesicle composition which can stably be compounded with a ceramide compound to provide a ceramide-containing composition which is excellent in a moisture-retaining effect and in temporal stability and can also be used as an external preparation for skin and to provide an external preparation for skin, compounded with the ceramide-containing composition.SOLUTION: This vesicle composition is characterized by comprising the following components (a) to (f): (a) an N-acyl-L-glutamic acid, (b) a ceramide compound, (c) a sterol compound, (d) an alkali agent, (e) a polyhydric alcohol, and (f) water.COPYRIGHT: (C)2008,JPO&INPIT【課題】本発明は、セラミド類を安定に配合することができる新規ベシクル組成物を開発し、さらに皮膚外用剤としても保湿効果および経時安定性に優れたセラミド含有組成物およびセラミド含有組成物を配合した皮膚外用剤を提供すること。【解決手段】次の成分(a)~(f);(a)N-アシル-L-グルタミン酸(b)セラミド類(c)ステロール類(d)アルカリ剤(e)多価アルコール(f)水を含有するベシクル組成物を提供すること。【選択図】なし