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HAEMOSTATIC WOUND DRESSING
专利权人:
HAEMOSTATIX LIMITED
发明人:
WALKER GREG,MIDDLETON SARAH MARGARET
申请号:
IN6952DEN2014
公开号:
IN6952DEN2014A
申请日:
2014.08.19
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
Haemostatic wound dressings are described. The dressings comprise a non colloidal porous dressing material and a plurality of fibrinogen binding peptides immobilised to the non colloidal porous dressing material wherein each fibrinogen binding peptide comprises: an amino acid sequence Gly Pro Arg Xaa (SEQ ID NO: 1 ) at an amino terminal end of the peptide wherein Xaa is any amino acid other than Val preferably Pro Sar or Leu; or an amino acid sequence Gly His Arg Xaa (SEQ ID NO: 2) at an amino terminal end of the peptide wherein Xaa is any amino acid other than Pro. The dressings are able to accelerate haemostasis without requiring enzymatic activity. In particular the dressings to do not rely on the action of exogenous thrombin and can be stored long term at room temperature in solution. Methods of making the dressings and use of the dressings to control bleeding are also described.
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