암을 치료하기 위한 거대 환형 MCL1 억제제

• 收藏
• 分享

专利权人:

아스트라제네카 아베

发明人:

허드, 알렉산더,벨몬트, 매튜, 앨런,양, 원잔,세크리스트, 존, 폴,로빈스, 다니엘, 윌리엄,카즈머스키, 스티븐, 리,우, 더둥,펑, 보,요하네스, 제프리,램브, 미쉘, 라우레,예, 칭,정, 샤오란

申请号：

KR1020187033540

公开号：

KR1020180135030A

申请日:

2017.04.21

申请国别(地区):

KR

年份:

2018

代理人:

摘要：

The invention discloses a kind of compounds, are [27.7.1.14,7.011,15.016,21.020,24.030,35] octatriaconta-1 (37), 4 (38), 6,11,14,16,18,20,23,29,31,33,35-tridecaene-23- carboxylic acids (formula I) and enantiomer and its pharmaceutically acceptable salt. Also disclose 17 chloros -5,13 with such compound and composition, 14,22- tetramethyl -28-5,13,14,22-2,9-dithia-5,6,12,13,22-pentaazaheptacyclo [27.7.1.14,7.011,15.016,21.020,24.030,35] pharmaceutical compositions of octatriaconta-1 (37), 4 (38), 6, the method for 11,14,16,18,20,23,29,31,33,35-tridecaene-23- carboxylic acids and enantiomer and its pharmaceutically acceptable salt and treating cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/