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High-purity phospholipids
专利权人:
发明人:
Gideon Halperin,Eti Kovalevski-Ishai
申请号:
US13833940
公开号:
US09006217B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids, are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorus-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby. Further disclosed is substantially pure 1-hexadecyl-2-(4′-carboxy)butyl-sn-glycero-3-phosphocholine (CI-201).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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