OR, YAT SUN,MA, JUN,WANG, GUOQIANG,LONG, JIANG,WANG, BIN
申请号:
MYPI 2013700450
公开号:
MY164754A
申请日:
2011.09.20
申请国别(地区):
MY
年份:
2018
代理人:
摘要:
THE PRESENT INVENTION DISCLOSES COMPOUNDS OF FORMULA I OR PHARMACEUTICALLY ACCEPTABLE SALTS, ESTERS, OR PRODRUGS THEREOF: WHICH INHIBIT SERINE PROTEASE ACTIVITY, PARTICULARLY THE ACTIVITY OF HEPATITIS C VIRUS (HCV) NS3-NS4A PROTEASE. CONSEQUENTLY, THE COMPOUNDS OF THE PRESENT INVENTION INTERFERE WITH THE LIFE CYCLE OF THE HEPATITIS C VIRUS AND ARE ALSO USEFUL AS ANTIVIRAL AGENTS. THE PRESENT INVENTION FURTHER RELATES TO PHARMACEUTICAL COMPOSITIONS COMPRISING THE AFOREMENTIONED COMPOUNDS FOR ADMINISTRATION TO A SUBJECT SUFFERING FROM HCV INFECTION. THE INVENTION ALSO RELATES TO METHODS OF TREATING AN HCV INFECTION IN A SUBJECT BY ADMINISTERING A PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUNDS OF THE PRESENT INVENTION.