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PRENATAL THERAPY TO INDUCE IMMUNE TOLERANCE
专利权人:
发明人:
Roberto Mallone,Sebastien Lacroix-Desmazes
申请号:
US15190272
公开号:
US20170072032A1
申请日:
2016.06.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Constructs and methods for inducing immune tolerance during gestation, e.g. in utero, are provided. The constructs comprise a moiety that targets and binds to the neonatal Fc receptor (FcRn) and a moiety comprising an antigen of interest for which immune tolerance is desired. Administration of the constructs to a fetus during gestation results in immune tolerance, e.g. to antigens that otherwise elicit an unwanted immune response such as an autoimmune reaction.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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