Growing systems may include a number of modular growing chambers with integrated support columns that eliminate the need for an external support frame and which provide a simple way to remove chambers from a stack for harvesting. Pins provided on the support columns ensure alignment and provide for easy removal of a lower chamber by first supporting the stack and slightly lowering it relative to the stack. The chambers may be provided with one or more removable access panels that provide access to the interior of the chambers for harvesting from the plant section inside. The chamber structure supports harvesting processes that permit harvesting of chambers in sequence by sequentially accessing the interior of successive chambers and harvesting a production portion from the plant section inside. Plant production can be made continuous and perpetual by sequentially harvesting from successive chambers and repeating the process after a plant section in a first chamber has regenerated another production portion. The chambers may include one or more plant guides for guiding growth of the plant sections within each chamber.