A motorized surgical instrument (10) comprising a linearly driven load unit (40), a motorized handle assembly (20) that provides a rotary drive and an adapter (30) configured to interface between and interconnect the load unit and the handle assembly, the adapter comprising an envelope (31), characterized in that the adapter further comprises: a cam drum (62) within the envelope defining a longitudinal axis, the cam drum being capable of being moved to along the longitudinal axis between a retracted position and an advanced position with respect to the envelope, the cam drum being supported for rotation about the longitudinal axis and defining first and second radial cam grooves (63, 64) around a surface external thereof, the first cam slot defining a first profile and the second cam slot defining a second profile; a first linear actuator (65a) within the enclosure that includes a first cam follower (66c) disposed in the first cam slot, the first linear actuator being supported for its movement between advanced and retracted positions with respect to the cam drum a along an axis parallel to the longitudinal axis in response to the rotation of the cam drum around the longitudinal axis; and a second linear actuator (65b) within the enclosure that includes a second cam follower (66c) in the second cam slot, the second linear actuator being supported for its movement between advanced and retracted positions with respect to the cam drum a along an axis parallel to the longitudinal axis in response to the rotation of the cam drum around the longitudinal axis.Un instrumento quirúrgico (10) motorizado que comprende una unidad de carga (40) accionada linealmente, un conjunto de mango motorizado (20) que proporciona un accionamiento rotatorio y un adaptador (30) configurado para hacer de interfaz entre e interconectar la unidad de carga y el conjunto de mango, comprendiendo el adaptador una envolvente (31), caracterizado por que el adaptador comprende, además: un tambor de le