Syringe (10) comprising: - A Body of syringe (20) extending along a longitudinal AXIS (A1) from a Lower End (20a) to a Higher End (20b),Allowing the lower End (20a) The Body of the syringe (20) Fixing a Needle or Cannula and taking the Top End (20b) body of the syringe (20) an Upper Opening (20c) QEU allows the introduction of a plunger in the body of the syringe (20),The syringe Body having an inner Wall (20) and (21) including at least a First CAP (32) located along the Inner Wall of the syringe Body (21) (20) near the opening....R (20c), being the first stop (32) adapted to allow at least a First Surface (22) in the Hollow Inner Wall of the syringe Body (21) (20),(100) and a plunger Sliding along the Inner Wall of the syringe Body (21) (20) along the longitudinal AXIS (A1),The Piston comprises a piston Head (100), (110) and a Drive rod (120) connected to the Top End (110B) of the piston Head (110)The Upper End (110B) of the piston Head (110) being turned towards the Upper opening of the body of the syringe (20c) (20), Rod Drive (120) (100) includes a Plunger(121) on its Outer Surface, at least a First zipper (122) arranged longitudinally along the Rod Drive (120)Understanding the first Zipper teeth (122) outstanding (122A) being the first stop (32) and protruding teeth (122A) formed and constituted to,At the time of the Rise of the Plunger (100) in the body of the syringe (20) from a low position in which the Plunger Head (110) is near the lower end of the syringe Body (20a) (20)Is a high position in which the Plunger Head (110) is close to the Upper End (20b) body of the syringe (20), when the first stop (32) and the first zipper (122) are encountered.Allow the Plunger Ascent (100) a Tooth to Tooth along the body of the syringe (20),When the syringe (10) wherein the first stop (32) and protruding teeth (2) are similarly shaped and formed to prevent any decline in the Plunger (100) by PPressure on the Rod Drive (120) except for uncoupling the first zipper (122) b