An apparatus and a system for guiding a cleaning implement and a method of use thereof are provided. The apparatus comprises a body and a guide. The body comprises a surface configured to be received by a valve port of a medical device. The guide comprises a first guide port, a second guide port, and a conduit. The first guide port is disposed at a first position on the surface of the body and the second guide port is disposed at a second position on the surface of the body that is different from the first position. The second position is configured to align the second guide port with a lumen of the medical device. The conduit extends through the body from the first guide port to the second guide port. The conduit comprises a contour configured to guide the cleaning implement between the first guide port and the lumen.
