Cosmetic compositions comprising creatine and low amounts of a biotinylated tripeptide are disclosed, as well as methods of using such compositions to improve the appearance of eyelashes. These compositions are believed to have synergistic modulatory activities in a number of biochemical pathways implicated in lash health.本發明係關於包含肌酸及少量生物素標記三肽之化妝組合物,以及使用該等組合物改善睫毛外觀之方法。咸信此等組合物在與睫毛健康有關連之許多生物化學路徑中具有協同調節活性。