Embodiments of the invention relate to liposomes comprising: a lipid bilayer having an internal cavity； a therapeutic agent within the internal cavity configured to modify expression or degradation of WASp in a cell； and a targeting moiety external to the lipid bilayer configured to target an extracellular domain of a cell. Embodiments of the invention relate to methods of treatment of disease comprising administering the liposomes. Novel pharmaceutical compositions are also disclosed.
