Developed are a composition for inhibiting IL-8 expression which can be used daily and which is stable and safe, and an external preparation for the skin, a pharmaceutical composition and a food composition containing same. The present invention provides a composition for inhibiting IL-8 expression which comprises 1 type or more of a compound selected from a group consisting of a D-methionine, a derivative thereof and/or a salt thereof. The composition may be an external preparation for the skin, a pharmaceutical composition for treating and/or preventing skin diseases, or a food composition. This composition may be used to treat diseases in which IL-8 is expressed, but in which IL-6 and TNF-a are not expressed.
