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compounds and compositions as raf kinase inhibitors
专利权人:
NOVARTIS AG
发明人:
BENJAMIN R. TAFT,MATTHEW T. BURGER,SAVITHRI RAMURTHY
申请号:
BR112017004741
公开号:
BR112017004741A2
申请日:
2015.09.11
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to a compound of formula I: wherein x, y, z, r1 and r2 are as described in the present invention, and salts thereof and therapeutic uses of these compounds for the treatment of disorders associated with the activity of the present invention. of raf kinase. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic coagent.a presente invenção refere-se a um composto de fórmula i: em que x, y, z, r1 e r2 são como descritos na presente invenção, e os sais dos mesmos e usos terapêuticos destes compostos para o tratamento de distúrbios associados com a atividade de raf quinase . a presente invenção proporciona ainda composições farmacêuticas compreendendo estes compostos, e composições compreendendo estes compostos e um coagente terapêutico.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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