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ORAL DOSAGE FORM FOR ENHANCED SOLUBILIZATION OF A POORLY SOLUBLE ACTIVE AGENT AND METHOD OF PREPARATION
专利权人:
OYSTERSHELL NV
发明人:
Bart Rossel
申请号:
US16476019
公开号:
US20190343849A1
申请日:
2018.01.08
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides and oral dosage form comprising a granular phase and a non-granular phase, whereby said granular phase is comprised of a therapeutically effective amount of pharmaceutically active agent, a gas forming agent and a hydrophilic polymer. Such dosages are found to provide fast dissolution rates for ingredients having low solubility in water. In addition, the present invention provides a method of preparation thereof.
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