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Selective PYY compounds and uses thereof
专利权人:
Novo Nordisk A/S
发明人:
Soeren Oestergaard,Kilian Waldemar Conde Frieboes,Birgit Wieczorek,Jens Kaalby Thomsen,Birgitte Schjellerup Wulff,Carsten Jessen
申请号:
US14540474
公开号:
US20150152150A1
申请日:
2014.11.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.
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