GEORGE ANTHONY CONDER,DEBRA JEAN WOODS,KEVIN EVANS,PATRICK F. M. MEEUS
申请号：
ARP120103892
公开号：
AR088461A1
申请日:
2012.10.18
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
Requirement 1: a method for the treatment of parasitic infections in animals requiring treatment, characterized by the effective management of a formula compound (1) in animals,Veterinary stereoisomers or salts are there: R1,R2,R3,R83088 and r83099 were selected from h, halo, CN and cf832303 respectively；Methyl, methoxy, ocf8323 and sc832323；wherein the compound is effective in treating endoparasitic infection. Claim 3: The method according to claim 2, characterized in that the compound of formula (1) is selected from the group consisting of: N- {1-cyano-2- [3-cyano-5- (trifluoromethyl) phenoxy ] -methylethi} -4- (pentafluorothio) -benzamide； N- [2- (2-bromo-5-cyanophenoxy) -1-cyano-1-methylethI] -4- (pentafluorothio) -benzamide； and @@@ N - {(1S) 1-cyano-2- [4-cyano-2- (trifluoromethyl) phenoxy] -1-methylethyl} -4-pentafluorothiobenzamide, a stereoisomer thereof,It's either an acceptable veterinary formula salt or this stereoisomer Requirement 4: a method for the treatment of parasitic infections in animals requiring treatment, characterized by the effective management of a formula compound (2) in animals,Veterinary stereoisomers or salts, where R1 74911,R74959,RS758080,R174969 and r749779 were selected from the group consisting of hydrogen, halogen and cf832323, respectively；-8.8323,methyl and hydroxyl. Claim 15: A compound characterized in that it is selected from the group consisting of: N- {1-cyano-2- [5-cyano-2- (4-fluorophenoxy) phenoxy] -1-methylethium} -4- (pentafluorothio) benzamide ； N- {2- [2- (4-chloro-2-fluorophenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl) -4- (pentafluorothio) benzamide； N- {2- [2- (4-chlorophenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl} -4- (pentafluorothio) benzamide； N- (1-cyano-2- {5-cyano-2- [4- (trifluoromethyl) phenoxy] phenoxy} -1-methylethyl) -4- (pentafluorothio) benzamide. N- {2- [2- (2-chloro-4-methylphenoxy) -5-cyanophenoxy] -1-cyano-1-methylethyl} -4- (pentafluorothio) benzamide；N - {1-cyano-2 - [5-cyano-2 - (2,4-dim
