Disclosed is a novel anti-allergic agent which can act on allergic diseases effectively and has reduced adverse side effects. The anti-allergic agent comprises an RXR agonist as an active ingredient. The RXR agonist to be used as the active ingredient for the anti-allergic agent can prevent allergic diseases through a different mechanism of action from that of the glucocorticoid receptor activation activity of a steroid. While a steroid produces various adverse side effects through a glucocorticoid receptor (GR) which is one of nuclear receptors, the RXR agonist does not act on a GR and therefore can be used as a novel anti-allergic agent that can act on allergic diseases effectively and has reduced adverse side effects.
