The disclosure is partly guided to a kind of method for being used to determine whether that there is a main body of cancer to be among risk for the developing transfer of cancer. In one embodiment, method includes (a) obtaining a biological sample from the main body with cancer (b) CCR5 cooperation bases at least one CCR5 expressions and/or expression in the biological sample is determined If (c) compared in CCR5 cooperation bases at least one the CCR5 expressions and/or expression in a control sample, at least one expression of CCR5 and/or CCR5 determining in step (b) cooperations base increases, so for the developing transfer of cancer, main body is accredited as possible be in danger.