The present invention concerns a compound of following formula (I): where: Ri is H or OH ,- R 2is a (Ci- C6)alkyl , COOH , COO - ((Ci- C6)alkyl) or thiazolyl group- R3 is H or a (Ci- C6)alkyl group , and R is: � a straight -chain or branched saturated or unsaturated hydrocarbon group having 1 to 8 carbon atoms substituted by one or more groups chosen from among OH and NR5R6 ,. (CH2CH2Xi)(CH2CH2X2)a2(CH2CH2X3)a3(CH2CH2X4)a4(CH2CH2X5)a5R 7 ,.an aryl (Ci- C8)alkyl group substituted by one or more groups chosen from among OH and NRR groups , or . a heterocycle- (Ci- Cs)alkyl group optionally substituted by one or more groups chosen from among (Ci- C6)alkyl , OH and NR12R13 groups , or a pharmaceutically acceptable salt , hydrate or solvate thereof , and its uses in particular for the treatment of cancer , pharmaceutical compositions containing the same and the preparation methods thereof.
