This invention relates to preparations comprising a butyrate salt for enteral administration for use in the treatment of conditions and diseases that are not diseases or conditions of the intestine and/or are associated with systemic inflammation. Preparations comprising a butyrate salt for enteral administration were found useful in the treatment of osteoarthritis, arteriosclerosis, rheumatism, psoriasis, multiple sclerosis, Alzheimer's' disease, Parkinson's disease, migraine, autism, depression, impaired kidney functioning, idiopathic subfertility, recurrent abortion, recurrent implantation failure, hangovers, and gout.
