SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;ARAGON PHARMACEUTICALS, INC.
发明人:
SMITH, NICHOLAS D.,HERBERT, MARK R.,OUERFELLI, OUATHEK,DILHAS, ANNA
申请号:
CA3055660
公开号:
CA3055660A1
申请日:
2013.06.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Described herein are amorphous and crystalline forms of the androgen receptormodulator4-[7-(6-cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide. Also described are pharmaceutical compositions suitable foradministration toa mammal that include the androgen receptor modulator, and methods of usingthe androgenreceptor modulator, alone and in combination with other compounds, fortreating diseases orconditions that are associated with androgen receptor activity.