藉由抑制ＰＡＲ４天然反股轉錄本治療ＰＡＲ４相關疾病农业专利-农业学术服务平台

发明人:: COLLARD, JOSEPH,柯拉德　约瑟夫,柯拉德　約瑟夫,KHORKOVA SHERMAN, OLGA,寇可维　薛曼　欧嘉,寇可維　薛曼　歐嘉,COITO, CARLOS,柯多　卡洛斯,柯拉德约瑟夫,柯拉德約瑟夫,寇可维薛曼欧嘉,寇可維薛曼歐嘉,柯多卡洛斯

摘要：: The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of PAR4, in particular, by targeting natural antisense polynucleotides of PAR4. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of PAR4.本發明係關於藉由具體而言靶向PAR4之天然反股多核苷酸來調節PAR4之表現及/或功能的反股寡核苷酸。本發明亦係關於對該等反股寡核苷酸之鑑別及其在治療與PAR4表現有關之疾病及病症中之用途。