In vivo model of human small intetine using pluripotent stem cells and methods of making and using same

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专利权人:

Childrens Hospital Center; d/b/a Cincinnati Childrens Hospital Medical Center

发明人:

Wells, James M.,Helmrath, Michael A.,Mahe, Maxime Mickael,Watson, Carey L.,Munera, Jorge

申请号：

AU2015331848

公开号：

AU2015331848A1

申请日:

2015.10.16

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESCs) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/