ZHAO, QIAN,YIFRU, AREGAHEGN,WAN, LIFENG,TAFT, BENJAMIN R.,SUTTON, JAMES CLIFFORD,POON, DANIEL,MARX, VANESSA,MANNING, JAMES R.,KOESTER, DENNIS CHRISTOFER,JAIM, RAMA
申请号：
ARP170102385
公开号：
AR109438A1
申请日:
2017.08.29
申请国别(地区):
AR
年份:
2018
代理人:
摘要：
1. Claim 1: a formula compound (1),a. A set of formulas (2), wherein the dotted line represents the link (1) connecting the set and the formula；G is h or a group selected between - C (o) r83044；-C (O) -OR-C (RG) -O-C (O) R-C (RG) -O-C (O) -OR-P (3DO) (OR)- (CRG) -O-P (3DO) (OR)-C (O) -N (R)y -C (RG) -O-C (O) N (R)where each R⁰ is independently H or a group selected from C₁₋₆ alkyl,fenilo piridilo cicloalquilo Cand a 3-6 membered heterocyclic ring containing one or two heteroatoms selected from N, O, and S as ring members； and each R⁰ that is not H is optionally substituted by one or two groups selected from halo, CN, -OH, amino, C₁₋₄ alkyl,COOR fenilo alcoxilo Chaloalkyl C₁₋₄,a. Halogenated alcoxyl c83217c83318324；and each RG is independently selected from H and C₁₋₄ alkyl；R1 is h, halo, CN, coor *,-CONR * ₂,or C₁₋₆-alkyl which is optionally substituted by one or two groups selected from -OR * and -NR * ₂；R * is independently at each occurrence H or C₁₋₆-alkyl optionally substituted by -OR or -NR₂；Z1 is n, Z2 is C (R) 832222；O Z1 is ch, Z 2 is NR, O, s, O ch832222；Z3 is ch832222,Q, -CH₂-CH₂-,-Q-CH₂-,-C8322Q---CH₂-Q-CH₂- or -CH₂-CH₂-CH₂-；If you are already registered, please log in first.O S SO y SOR² is selected from H, halo, CN, C₁₋₄ alkyl optionally substituted by up to three groups independently selected from halo, CN, C₁₋₄ alkyl,-OR, haloalkoxy C₁₋₄,-No. 832222,And halogenated tar c831832421,o. Halide c8321c83318324；Each cubic meter is an alternative to any carbon atom containing Z2 and Z3 in the ring.It was selected from - or, halide c8321c83318324；haloalkoxy C₁₋₄,oxo CN -NRand C₁₋₄-alkyl optionally substituted by up to three groups independently selected from halo, CN, C₁₋₄-alkyl,-OR, haloalkoxy C₁₋₄,-No. 832222,a. Halogenated tar c831832421；N is 0-2； AR1 and ar2 respectively represent phenyl or 5-6 heterocycles, which contain 1-3 heteroatoms selected from n or s, or as ring members； AR1 and ar2 are free of up to 3 groups selected from halo, i.e. c833134 tar s
