The invention relates to antibacterial compounds of formula IIwherein U1represents N or CH, U2represents N or CH, U3represents N or CH, it being understood that at most two of U1, U2, U3can represent N at the same time V1represents N or CH, V2represents N, CH or C(OH) and V3represents N, CH or C(OH), it being understood that at most two of V1, V2and V3can represent N at the same time the dotted line “-----” represents a bond or is absent X represents CH or N and Q represents O or S. It further relates pharmaceutical compositions containing these compounds and the uses of these compounds in the manufacture of medicaments for the treatment of bacterial infections. These compounds are useful antimicrobial agents effective against a variety of human and veterinary pathogens including among others Gram-positive and Gram-negative aerobic and anaerobic bacteria.本發明係關於式I之抗菌化合物I其中U1表示N或CH,U2表示N或CH,U3表示N或CH,應瞭解,U1、U2、U3中之至多兩者可同時表示N; V1表示N或CH,V2表示N、CH或C(OH)且V3表示N、CH或C(OH),應瞭解,V1、V2及V3中之至多兩者可同時表示N;虛線「-----」表示鍵或不存在;X表示CH或N;且Q表示O或S。本發明進一步係關於含有該等化合物之醫藥組合物及該等化合物在製造用於治療細菌感染之藥劑中之用途。該等化合物係有效抵抗尤其包括革蘭氏陽性(Gram-positive)及革蘭氏陰性(Gram-negative)需氧及厭氧細菌之各種人類及獸類病原體之有用抗微生物劑。無
