Yong Gan,Chunliu Zhu,Sophie Zhai,Robert I. Schmitt,Ka Chun A. Chan
申请号:
US13254115
公开号:
US20120045485A1
申请日:
2009.06.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An osmotic dosage form which comprising:(a) a core comprising a biologically active ingredient(b) a semi-permeable membrane covering said core and(c) at least one passageway through the semi-permeable membrane,wherein the semi-permeable membrane comprises ethyl cellulose, an acrylic or methacrylic polymer and a water-soluble plasticizer with the proviso that the semi-permeable membrane comprises no or not more than 15 weight percent of a water-soluble material excluding any water-soluble plasticizer, based on the total dry weight of the semi-permeable membrane.