Agents and methods relating to reducing resistance to apoptosis-inducing death receptor agonists

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专利权人:

ザ ユーエービー リサーチ ファンデーション

发明人:

チョウ， トン,キンバリー， ロバート ピー．,チョウ, トン,キンバリー, ロバート ピー.

申请号：

JP2007554179

公开号：

JP5562521B2

申请日:

2006.01.31

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist. Also provided are methods of screening for biomarkers resistance of and monitoring resistance to death receptor agonists. Also provided are methods of selectively inducing apoptosis in a target cell, treating a subject with cancer, autoimmune or inflammatory diseases, comprising administering compositions provided herein. Further provided are compositions comprising agents that modulate CARD containing proteins.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/