INFLUENZA VIRUS MUTANT EXPRESSING A HAEMAGGLUTININ PROTEIN WITHOUT FUNCTIONAL SIGNAL SEQUENCE FOR USE AS VACCINE

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专利权人:

发明人:

申请号：

EP12780518.2

公开号：

EP2758525A2

申请日:

2012.09.21

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides a modified influenza virus wherein the RNA of the haemagglutinin gene has been modified such that the haemagglutinin signal sequence is not expressed and the virus produces a haemagglutinin protein that lacks a functional signal sequence. The invention further provides composition comprising the modified virus and uses of the modified virus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/