A kind of method and system is disclosed, for assessing neurological disease using at least one motion sensor, is configured to attach to ontology attachment, memory has (multiple) sensor, for exercise as defined in the exercise data during periodically recording It is used to analyze the progress neurological disease of the variation assessment tumour of exercise data over time with processor. In one embodiment, neurological disease is that ALS and at least four motion sensors are used, so that the arm and leg of each patient have relevant sensor. The sensor can be the movement period stipulation of accelerometer measures displacement, the relevant limbs of velocity and acceleration. For example, the variation of patient can be classified as ALS patient and/or prediction development rate with specification and analysis with implementing to take exercise to a series of lifting limbs trainings are repeated or measurement limb tremor is associated.