GLUTAMATE DEHYDROGENASE IN IDH1- AND IDH2-MUTATED CANCERS

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专利权人:

Duke University

发明人:

Hai Yan,Matthew Waitkus

申请号：

US14843645

公开号：

US20160068610A1

申请日:

2015.09.02

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Expression of GLUD1, GLUD2, or both is tested in gliomas, leukemias, or suspected gliomas and leukemias. Up-regulation of expression is found in IDH1/IDH2 mutant cancers. Inhibition of GLUD1, GLUD2, or both can be used therapeutically to inhibit cancer growth. Assays for GLUD1, GLUD2, or both GLUD1 expression can measure RNA or protein or enzyme activity, for example.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/