The present invention provides a needleless syringe having, accommodated therein, a pharmaceutical preparation containing genes and/or analogues thereof. A needleless syringe comprising: a medical agent chamber 22 having one or multiple nozzle bore(s) 25 and accommodated with a medical agent L, and a syringe main body 12 being provided with pressure application means 32 to apply pressure on the medical agent L toward a direction of the nozzle bore (s) 25 and effect emission of the medical agent L through the nozzle bore (s) 25, wherein the medical agent L is a pharmaceutical preparation containing genes and/or analogues thereof. Examples of the medical agent L include pharmaceutical preparation containing HGF gene and pharmaceutical preparation containing NF-ºB decoy oligonucleotide.本發明係提供一種收容含有基因及/或其類似體之醫藥製劑之無針注射器。該無針注射器,係為一種包括具有一個或複數個噴嘴孔25並收容有藥劑之藥劑室22、以及具備將該藥液L朝噴嘴孔25的方向推壓以從上述噴嘴孔25噴射藥液L用之推壓機構32的注射器本體12之無針注射器;其中之藥液L係含有基因及/或其類似體之醫藥製劑。藥液L的例子,舉例來說,例如可以是含有HGF基因之醫藥製劑、以及NF-κ B引誘體寡核苷酸之醫藥製劑等。
