LACRAMPE, JEAN FERNAND ARMAND,赖曼德,賴曼德,MEYER, CHRISTOPHE,克里斯,LIGNY, YANNICK AIME EDDY,李爱迪,李愛迪,CSOKA, IMRE CHRISTIAN FRANCIS,卡法兰,卡法蘭,VAN HIJFTE, LUC,凡路西,ARTS, JANINE,尔珍妮,爾珍妮,SCHOENTJES, BRUNO,史柏
申请号:
TW094132574
公开号:
TWI372758B
申请日:
2005.09.21
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R1, R2, R3, R4, R5, R6, R7, X, Y, Q and Z have defined meanings.本發明提供式(I)化合物,彼等作為p53-MDM2相互作用之抑制劑以及包含該式(I)化合物之藥學組成物,;(I);其中n,m,p,s,t,R1,R2,R3,R4,R5,R6,R7,X,Y,Q及Z具有所定義之意義。