A novel anti-transferrin receptor antibody that crosses the blood-brain barrier

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专利权人:

ＪＣＲファーマ株式会社

发明人:

薗田 啓之,森本 秀人,越村 友理,木下 正文,高木 春奈,由井 佳子

申请号：

JP2015554972

公开号：

JP6616189B2

申请日:

2014.12.24

申请国别(地区):

JP

年份:

2019

代理人:

摘要：

Disclosed are novel anti transferrin receptor antibody that can pass through the blood-brain barrier, a fusion protein comprising a protein necessary to be brought into function in the central nervous system and the antibody, and method of their production. The fusion protein comprises amino acid sequences of an anti-human transferrin receptor antibody that recognizes an amino acid sequence selected from the group consisting of SEQ ID NOs:1, 2, and 3, and of other protein that is bound thereto on the C- terminal side.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/