The present invention provides a device for delivering a predetermined volume of a substance, within at least one body cavity of a subject, comprising a predefined volume for containing the predetermined volume of the at least one substance； a delivery end for placement in proximity to the body cavity； the delivery end comprises at least one orifice of diameter D [mm]； a valve mechanically connectable to the container, characterized by at least two configurations: (i) an active configuration in which the valve enables delivery of predetermined amount Msub of the substance； and, (ii) an inactive configuration, in which the valve prevents delivery of the predetermined amount Msub of the substance from the container to the body cavity； and a fluid tight chamber configured to contain predetermined volume Vgas of pressurized gas at a predetermined pressure, Pgas.
