The present invention relates to a novel peptide, a polynucleotide encoding the peptide, an expression vector comprising the polynucleotide, a pharmaceutical composition comprising the peptide, a quasi-drug composition, and a health functional food composition. To this end, the peptide is to treat dentine hyperesthesia and promote regeneration of dentine or pulpal tissues, and includes amino acid sequences represented by general formula 1, K-Y-R1-R2-R3-R4-R5-R6-R7-R8.본 발명은 신규한 펩타이드, 상기 펩타이드를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 발현벡터 및 상기 펩타이드를 포함하는 약학 조성물, 의약외품 조성물 및 건강기능성 식품 조성물에 관한 것이다.