2-amino-pyriidine derivatives useful as jnk inhibitors

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

BRADLEY E. LOE,DAVID MARK ROTSTEIN,DAVID MICHAEL GOLDSTEIN,ERIN M. O'BRIEN,HUMBERTO BARTOLOME ARZENO,LEYI GONG,LUBOV FILONOVA,TANIA SILVA,WYLIE SOLANG PALMER,YUN-CHOU TAN

申请号：

BR112012030931

公开号：

BR112012030931A2

申请日:

2011.06.01

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

Compounds of formula I or pharmaceutically acceptable salts thereof, wherein R5 is a group of formula (a) or (b): and wherein m, n, p, q, X, Y, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity.

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