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ЭКСТРУДИРОВАННАЯ СИСТЕМА ДОСТАВКИ
专利权人:
ФИРМЕНИШ СА (CH)
发明人:
ГРЕГСОН Кристофер М. (US),СИЛЛИК Меттью П. (US)
申请号:
RU2013157160/13
公开号:
RU2013157160A
申请日:
2012.06.15
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. The extruded delivery system comprising: (a) encapsulating medium soderzhaschiyi) crystalline component consisting of a material having a Tg below 30 ° C when it is in the amorphous state, and ii) an amorphous component in the vitreous state and (b) an encapsulated liquid active ingredient.2. The delivery system of claim 1, wherein the crystalline component is erythritol, mannitol, sorbitol, xylitol or smesyu.3. The delivery system of claim 2, wherein the crystalline component is eritritom.4. The delivery system of claim 1, wherein the active ingredient is at a temperature of 45 ° C and 1 atm is zhidkostyu.5. The delivery system of claim 1, wherein the non-crystalline component having a Tg above 30 ° C.6. The delivery system of claim 1, wherein the non-crystalline component is selected from polysaccharides, proteins and disaccharides having a Tg above 30 ° C.7. The delivery system of claim 1, wherein the non-crystalline component is one or more hydrogenated starch hydrolysates having a number average degree of polymerization (DPn) of between 5 and 100, or a number average molecular weight (Mn) between 800 and 16,000 Da.8. The delivery system of claim 1, wherein the crystalline component (i) is present in an amount between 10 and 90 wt.% relative to the total dry weight of components (i) and (ii) .9. The delivery system of claim 8, wherein the crystalline component (i) is present in an amount of at least 30 wt.% relative to the total dry weight of components (i) and (ii) .10. The delivery system of claim 1, comprising, in addition, emulgator.11. The delivery system of claim 9, wherein the emulsifier is selected from lecithin, modified lecithins, mono- and diglycerides of fatty acids, sugar esters1. Экструдированная система доставки, содержащая:(a) инкапсулирующий носитель, содержащийi) кристаллический компонент, состоящий из материала, имеющего Tg ниже 30°C при его нахождении в аморфном состоянии, иii) аморфный компонент в застеклованном состоянии и(b) инкапсулиро
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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