Richard A. Young,Warren Whyte,Denes Hnisz,Jakob Loven,Heather Hoke,David Orlando,Charles Y. Lin,Tony Lee
申请号:
US14523560
公开号:
US09181580B2
申请日:
2014.10.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).