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PHARMACEUTICAL FORMULATION CONTAINING OPIOID AGONIST, OPIOID ANTAGONIST AND GELLING AGENT
专利权人:
Purdue Pharma L.P.;THE P.F. LABORATORIES, INC.;PURDUE PHARMACEUTICALS L.P.
发明人:
Benjamin Oshlack,Curtis Wright,Christopher Breder
申请号:
US15724869
公开号:
US20180021330A1
申请日:
2017.10.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid.
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