STICHTING TOP INSTITUTE PHARMA;N.V. ORGANON;VRIJE UNIVERSITEIT MEDISCH CENTRUM;ACADEMISCH MEDISCH CENTRUM;RIJKSUNIVERSITEIT GRONINGEN;ACADEMISCH ZIEKENHUIS GRONINGEN;PEPSCAN HOLDING N.V.
发明人:
MEDEMA, JAN PAUL,EENENNAAM, VAN HANS,GUADAGNOLI, MARCO,KIMBERLEY, FIONA CLARE,PHAN, UYEN TRUONG
申请号:
CA2754127
公开号:
CA2754127C
申请日:
2010.02.23
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to a bindingcom-pound which binds to human APRIL. More specifically thein-vention provides, compositions of anti-APRIL specificanti-bodies and methods to use such antibodies in modulating thebiological activity APRIL, particularly in inflammatorydis-eases, inhibition of cell proliferation and cancer.