ANTICORPS ANTI-CD11A HUMANISES

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专利权人:

GENENTECH; INC.

发明人:

JARDIEU, PAULA M.,PRESTA, LEONARD G.

申请号：

CA2272842

公开号：

CA2272842C

申请日:

1997.10.20

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Humanized anti-CD11 a antibodies and various uses therefor are disclosed. Thehumanized anti-CD11aantibody may bind specifically to human CD11a I-domain, have an IC50(nM) valueof no morethan about 1nM for preventing adhesion of Jurkat cells to normal humanepidermal keratinocytes expressingICAM-1, and/or an IC50 (nM) value of no more than about 1nM in the mixedlymphocyte response assay.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/