One aspect of the present invention isGold nanoparticles AndThe surface of the gold nanoparticles was treated with BIBB (Bis [2-(2-bromo isobutyryloxy) undecyl] disulfide as an initiator and DAMA (2-dimethylamino) ethyl methacrylate and HEMA (2-hydroxyethyl methacrylate) Polymer membrane gold nanoparticles comprising a polymer membrane formed by an initiating polymer living polymerization (SI-ATRP) reaction, complexes comprising the polymer membrane gold nanoparticles and an anticancer agent, a pharmaceutical composition for treating cancer comprising the complex, and a process for their preparation 본 발명의 일 양상은 금 나노입자 및 상기 금 나노입자 표면상에 BIBB (Bis[2-(2-bromo isobutyryloxy) undecyl] disulfide)를 개시제로 하고 DAMA (2-(dimethylamino)ethyl methacrylate) 및 HEMA (2-hydroxyethyl methacrylate)를 단량체로 하는 표면개시고분자리빙중합 (SI-ATRP) 반응에 의해 형성된 고분자막을 포함하는 고분자막 금 나노입자, 그 고분자막 금 나노입자 및 항암제를 포함하는 복합체, 그 복합체를 포함하는 암 치료용 약학 조성물, 및 이들의 제조방법을 제공한다.
