The present invention deals with an alternative interfacial polymerization process of microencapsulation, microcapsules produced thereof, microencapsulated agrochemicals, pharmaceuticals, catalysts and phase transfer materials, and formulations thereof, by means of microcapsules and starting materials with much lower toxicological profile than customary rmicroencapsulation materials, and with the participation of acetylene carbamide derivatives in the final structure of the microcapsules wall.