UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS;연세대학교 원주산학협력단;KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES;한국원자력의학원;한국원자력의학원;연세대학교 원주산학협력단
发明人:
KIM JUNG YOUNG,김정영,SHIN UN CHUL,신운철,SEO JONG BUM,서종범,PARK JI AE,박지애,LEE KYO CHUL,이교철
申请号:
KR1020180059272
公开号:
KR1020190134084A
申请日:
2018.05.24
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
Provided are: perfluorocarbon nanoparticles comprising a core part including a perfluorocarbon mixture and a bio-compatible shell part; an ultrasonic contrast agent comprising the perfluorocarbon nanoparticles; and a method for manufacturing the perfluorocarbon nanoparticles. Perfluorocarbon nanoparticles according to an aspect can minimize self-vaporization by body temperature and blood circulation during in vivo administration, and can induce acoustic droplet vaporization by relatively low ultrasonic energy.과불화탄소 혼합물을 포함하는 코어(core)부; 및 생체친화성 막(shell)부를 포함하는 과불화탄소 나노입자, 상기 과불화탄소 나노입자를 포함하는 초음파 조영제 및 상기 과불화탄소 나노입자의 제조방법을 제공한다.