A reduced-pressure abdominal treatment system has an open-cavity treatment device for providing reduced-pressure treatment proximate a patient's abdominal contents； a deep-tissue closure device for applying a closing force on a deep-tissue wound on a patient's fascia； a surface-wound closure subsystem for providing a closing force on a surface wound on the patient's epidermis； and a reduced-pressure supply subsystem operable to develop a reduced pressure. Methods are also included.
