This creation provides an air-conditioning sterilization device for transportation vehicles. The air-conditioning device of the vehicle contains an air-conditioning system and several air ducts. The air-conditioning system is equipped with air inlets and outlets. The air ducts are connected to the air outlets of the air-conditioning system and are distributed. In a vehicle; it is characterized in that there is a quick assembly device outside the air-conditioning system, and a sterilization device is assembled with the quick assembly device. The sterilization device is accessible to the air inlet. The sterilization device includes a filter mechanism, a sterilization mechanism and a control device, The sterilization mechanism contains a negative ion generator and an ozone generator. The negative ion generator starts the negative ion generator when the air-conditioning system is started. The ozone generator is started by the control device. When the air-conditioning system is running, the filter mechanism and the negative ion will The air in the car is filtered and sterilized, and then output by the air duct, and at a specific time, the ozone generator is activated by the control device to sterilize the surface of the objects in the car.本創作係提供一種交通運輸車輛之空調殺菌裝置,其係車輛之空調裝置含有一冷氣系統及數風管,冷氣系統設有進氣口及出氣口,風管連通冷氣系統之出氣口,並分佈於車輛內;其特徵在於:於該冷氣系統外有一快組裝置,以快組裝置組裝一殺菌裝置,殺菌裝置通達於進氣口,殺菌裝置包含有一過濾機構、一殺菌機構及一控制裝置,殺菌機構含有一負離子產生器及臭氧產生器,負離子產生器隨著啟動冷氣系統時,一併啟動負離子產生器,臭氧產生器是以控制裝置作啟動,冷氣系統運行時,透過過濾機構及負離子將車內空氣過濾及殺菌,再由風管輸出,並針對特定時候,以控制裝置啟動臭氧產生器將車內各物件表面殺菌。